Huang Lab

The Huang Lab was established in 2009 at the University of Chicago and has since been active in conducting pharmacogenomic research. In 2017, our laboratory moved to the University of Minnesota, where we continue that research.

Our main research focus is translational pharmacogenomics with a particular interest in the pharmacogenomics of anticancer agents. By systematically evaluating the human genome and its relationships to drug response and toxicity, our goal is to develop clinically useful models that predict risk for adverse drug reactions and nonresponse prior to administration of chemotherapy. Specifically, the theme of our research evolved around the idea of cell-based pharmacogenomics, which utilizes in vitro models for biomarker discovery and prediction-model construction, followed by in vivo validation. We routinely use cell lines (derived from healthy and diseased individuals as well as commercially available cancer cell lines) and clinical samples to discover and functionally characterize genetic variation and gene, miRNA, and long noncoding RNA expression for their roles in drug sensitivity.

Lab Announcements

Congratulations to Amy!

We are proudly announcing that our lab memeber Amy has won the Louise M. Nutter Academic Excellence Award from the Department of Pharmacology. Congratulations!

Congratulations to Yingbo and Mei-chi (Judy)!

Congratulations on successfully passing your preliminary exams and becoming PhD candidates. Keep on kicking!

New Abstract and Presentation

Congratulations to Yingbo for the acceptance of his abstract titled "Sex differences in the expression and genetic regulation of drug metabolism and transporter genes in human liver" by the ASHG 2021 Annual Meeting. Yingbo will deliver an oral presentation of his work during the event in October. Stay tuned!

Congratulations to Dr. Robert Galvin on receiving the CCRF Emerging Scientist Award!

Our lab member, Dr. Robert Galvin has received the award which will allow him to conduct research on understanding the impact of genetic factors on the pediatric central nervous system malignancies. We look forward to continuing to work with you!

To see past announcements, visit our archives here!