Huang Lab

The Huang Lab was established in 2009 at the University of Chicago and has since been active in conducting pharmacogenomic research. In 2017, our laboratory moved to the University of Minnesota, where we continue that research.

Our main research focus is translational pharmacogenomics with a particular interest in the pharmacogenomics of anticancer agents. By systematically evaluating the human genome and its relationships to drug response and toxicity, our goal is to develop clinically useful models that predict risk for adverse drug reactions and nonresponse prior to administration of chemotherapy. Specifically, the theme of our research evolved around the idea of cell-based pharmacogenomics, which utilizes in vitro models for biomarker discovery and prediction-model construction, followed by in vivo validation. We routinely use cell lines (derived from healthy and diseased individuals as well as commercially available cancer cell lines) and clinical samples to discover and functionally characterize genetic variation and gene, miRNA, and long noncoding RNA expression for their roles in drug sensitivity.

Lab Announcements

We are Hiring!

Do you have a passion for computational biology and/or molecular biology? We are actively looking for two postdocs with expertise is such areas. To learn more and apply, click here!

Congratulations to Siddhika and Aritro on their Newest Publication!

Congratulations to Siddhika and Aritro on their newest commentary article on microRNA targeting in ovarian cancer! To read more, click here!

Congratulations, Aritro!

Congratulations to Aritro for his recent publication in Bioinformatics on the iMIRAGE package in R to impute microRNA expression using protein-coding genes! To read more, click here!

Congratulations, Alex!

Alex has been awaded a Scholar-in-training award from AACR to attend the Advancing Precision Medicine Drug Development conference in San Diego this upcoming January (2020)! Congratulations!

To see past announcements, visit our archives here!